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Metabolic Network Completion. Compute minimal completions to your draft net with reactions from a repair net.

Project description

Installation

You can install meneco by running:

$ pip install --user meneco

On Linux the executable script can then be found in ~/.local/bin

and on MacOS the script is under /Users/YOURUSERNAME/Library/Python/3.2/bin.

Usage

Typical usage is:

$ meneco.py draftnetwork.sbml repairnetwork.sbml seeds.sbml targets.sbml

For more options you can ask for help as follows:

$ meneco.py --h
    usage: meneco.py [-h] [--enumerate] draftnetwork repairnetwork seeds targets

    positional arguments:
      draftnetwork   metabolic network in SBML format
      repairnetwork  metabolic network in SBML format
      seeds          seeds in SBML format
      targets        targets in SBML format

    optional arguments:
      -h, --help     show this help message and exit
      --enumerate    enumerate all minimal completions

Samples

Sample files for the reconstruction of ectocarpus are available here: ectocyc.sbml, metacyc_16-5.sbml, seeds.sbml, targets.sbml

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