tedana: TE Dependent ANAlysis

TE-dependent analysis (tedana) is a Python library for denoising multi-echo functional magnetic resonance imaging (fMRI) data. tedana originally came about as a part of the ME-ICA pipeline, although it has since diverged. An important distinction is that while the ME-ICA pipeline originally performed both pre-processing and TE-dependent analysis of multi-echo fMRI data, tedana now assumes that you're working with data which has been previously preprocessed.

More information and documentation can be found at https://tedana.readthedocs.io.

Citing tedana

If you use tedana, please cite the following papers, as well as our most recent Zenodo release:

• DuPre, E. M., Salo, T., Ahmed, Z., Bandettini, P. A., Bottenhorn, K. L., Caballero-Gaudes, C., Dowdle, L. T., Gonzalez-Castillo, J., Heunis, S., Kundu, P., Laird, A. R., Markello, R., Markiewicz, C. J., Moia, S., Staden, I., Teves, J. B., Uruñuela, E., Vaziri-Pashkam, M., Whitaker, K., & Handwerker, D. A. (2021). TE-dependent analysis of multi-echo fMRI with tedana. Journal of Open Source Software, 6(66), 3669. doi:10.21105/joss.03669.
• Kundu, P., Inati, S. J., Evans, J. W., Luh, W. M., & Bandettini, P. A. (2011). Differentiating BOLD and non-BOLD signals in fMRI time series using multi-echo EPI. NeuroImage, 60, 1759-1770.
• Kundu, P., Brenowitz, N. D., Voon, V., Worbe, Y., Vértes, P. E., Inati, S. J., Saad, Z. S., Bandettini, P. A., & Bullmore, E. T. (2013). Integrated strategy for improving functional connectivity mapping using multiecho fMRI. Proceedings of the National Academy of Sciences, 110, 16187-16192.

Installation

Use tedana with your local Python environment

You'll need to set up a working development environment to use tedana. To set up a local environment, you will need Python >=3.6 and the following packages will need to be installed:

• numpy
• scipy
• scikit-learn
• nilearn
• nibabel
• mapca

You can then install tedana with

pip install tedana

Creating a miniconda environment for use with tedana

In using tedana, you can optionally configure a conda environment.

We recommend using miniconda3. After installation, you can use the following commands to create an environment for tedana:

conda create -n ENVIRONMENT_NAME python=3 pip mdp numpy scikit-learn scipy
conda activate ENVIRONMENT_NAME
pip install nilearn nibabel
pip install tedana

tedana will then be available in your path. This will also allow any previously existing tedana installations to remain untouched.

To exit this conda environment, use

conda deactivate

NOTE: Conda < 4.6 users will need to use the soon-to-be-deprecated option source rather than conda for the activation and deactivation steps. You can read more about managing conda environments and this discrepancy here.

You can confirm that tedana has successfully installed by launching a Python instance and running:

import tedana

You can check that it is available through the command line interface (CLI) with:

tedana --help

If no error occurs, tedana has correctly installed in your environment!

Use and contribute to tedana as a developer

If you aim to contribute to the tedana code base and/or documentation, please first read the developer installation instructions in our contributing section. You can then continue to set up your preferred development environment.

Getting involved

We :yellow_heart: new contributors! To get started, check out our contributing guidelines and our developer's guide.

Want to learn more about our plans for developing tedana? Have a question, comment, or suggestion? Open or comment on one of our issues!

If you're not sure where to begin, feel free to pop into Mattermost and introduce yourself! We will be happy to help you find somewhere to get started.

If you don't want to get lots of notifications, we send out newsletters approximately once per month though our TinyLetter mailing list. You can view the previous newsletters and/or sign up to receive future ones at https://tinyletter.com/tedana-devs.

We ask that all contributors to tedana across all project-related spaces (including but not limited to: GitHub, Mattermost, and project emails), adhere to our code of conduct.

Contributors

Thanks goes to these wonderful people (emoji key):

Logan Dowdle 💻 💬 🎨 🐛 👀	Elizabeth DuPre 💻 📖 🤔 🚇 👀 💡 ⚠️ 💬	Javier Gonzalez-Castillo 🤔 💻 🎨	Dan Handwerker 🎨 📖 💡 👀	Prantik Kundu 💻 🤔
Ross Markello 💻 🚇 💬	Taylor Salo 💻 🤔 📖 ✅ 💬 🐛 ⚠️ 👀	Joshua Teves 📆 📖 👀 🚧 💻	Kirstie Whitaker 📖 📆 👀 📢	Monica Yao 📖 ⚠️
Stephan Heunis 📖	Benoît Béranger 💻	Eneko Uruñuela 💻 👀 🤔	Cesar Caballero Gaudes 📖 💻	Isla 👀
mjversluis 📖	Maryam 📖	aykhojandi 📖	Stefano Moia 💻 👀 📖	Zaki A. 🐛 💻 📖
Manfred G Kitzbichler 💻	giadaan 📖

This project follows the all-contributors specification. Contributions of any kind welcome! To see what contributors feel they've done in their own words, please see our contribution recognition page.